Bergamot Phytosome

ID: bergamot_phytosome

Aliases: bergamot polyphenolic fraction phytosome, Citrus bergamia phytosome

Type: formulation

Route/form: oral supplement/extract unless otherwise specified

Status: supplement

Evidence level: human RCT

Best data tier: human controlled/review

Support scope: human

Source types: human_rct, systematic_review

Linked sources: 3

Broad outcomes: Cardiovascular / lipids / blood pressure, Fat loss / metabolic health

Reading note: These are curation notes anchored to linked sources, not a clinical recommendation or protocol.

Targets / mechanism

• lipid metabolism
• visceral fat
• citrus polyphenols

Optimization domains

• cardiovascular health
• lipids
• visceral fat
• supplement

Research basis

• A randomized placebo-controlled trial in overweight/obese class I subjects with mild hypercholesterolemia reported improved visceral fat and lipid profiles.
• Adds a higher-evidence botanical lipid-management entry than most extract claims.

Limits, risks, and missing evidence

• Formulation-specific phytosome results may not translate to generic bergamot products.
• Clinical role depends on baseline risk, diet, medications, and lipid targets.

Risk flags

• standardization uncertainty
• formulation specific
• drug interaction review
• medical monitoring

Linked papers, labels, and reviews

1. Bergamot phytosome improved visceral fat and plasma lipid profiles
   human_rct / pubmed_bergamot_phytosome_2021
   Randomized placebo-controlled trial in overweight/obese class I subjects with mild hypercholesterolemia.
2. Effect of bergamot on lipid profile in humans: A systematic review
   systematic_review / pubmed_bergamot_lipid_systematic_2020
   Human lipid-profile review for bergamot products; not specific to the phytosome formulation.
3. Clinical Pharmacology of Citrus bergamia: A Systematic Review
   systematic_review / pubmed_citrus_bergamia_clinical_review_2017
   Broader clinical-pharmacology review for Citrus bergamia derivatives and formulation caveats.