Cetoleic Acid Concentrate

ID: cetoleic_acid_concentrate

Aliases: 22:1n-11 concentrate, cetoleic acid

Type: compound

Route/form: oral supplement/food component unless otherwise specified

Status: supplement_or_food_component

Evidence level: human RCT

Best data tier: human controlled/review

Support scope: human, non-human/mechanistic

Source types: human_rct, preclinical

Linked sources: 2

Broad outcomes: Cardiovascular / lipids / blood pressure, Fat loss / metabolic health

Reading note: These are curation notes anchored to linked sources, not a clinical recommendation or protocol.

Targets / mechanism

• LDL cholesterol
• fatty-acid metabolism

Optimization domains

• cardiovascular health
• lipids
• dietary fat

Research basis

• A randomized double-blind clinical trial in adults with overweight or obesity reported lower serum LDL cholesterol after cetoleic-acid concentrate supplementation.
• Relevant to the repository's lipid-lowering food-component bucket.

Limits, risks, and missing evidence

• Effect size, durability, and comparison with established lipid therapies need careful extraction.
• Product composition and marine-oil context may matter more than isolated cetoleic acid alone.

Risk flags

• standardization uncertainty
• lipid monitoring
• formulation specific
• limited replication

Linked papers, labels, and reviews

1. Cetoleic acid concentrate decreased serum LDL-cholesterol in adults with overweight or obesity
   human_rct / lifescience_cetoleic_acid_ldl_2026
   British Journal of Nutrition randomized double-blind controlled clinical trial listing.
2. Herring oil rich in long-chain monounsaturated fatty acid lowers plasma lipids and modulates fatty acid composition, oxidation, and inflammation in rats
   preclinical / pubmed_cetoleic_herring_oil_lipids_2025
   Cetoleic-acid-rich herring-oil animal and in vitro source; supports lipid-metabolism plausibility adjacent to the human LDL trial.