Saskatoon Berry

ID: saskatoon_berry

Aliases: Amelanchier alnifolia, Saskatoon berry powder, Saskatoon berry polyphenols

Type: botanical_extract

Route/form: oral berry food, powder, or extract depending study/product

Status: food_or_supplement

Evidence level: early human

Best data tier: early human

Support scope: human, non-human/mechanistic, context

Source types: clinical_trial_registry, early_human, preclinical

Linked sources: 4

Broad outcomes: Cardiovascular / lipids / blood pressure, Fat loss / metabolic health, Gut / immune / inflammation

Reading note: These are curation notes anchored to linked sources, not a clinical recommendation or protocol.

Targets / mechanism

• berry polyphenols and anthocyanins
• short-chain fatty acids
• Prevotellaceae/Muribaculaceae-linked microbiome hypotheses

Optimization domains

• gut health
• microbiome
• metabolic
• cardiovascular health
• lipids
• blood pressure
• inflammation
• prebiotic

Research basis

• A recent human supplementation study reports cardiometabolic marker changes alongside gut microbiota and SCFA readouts.
• Rodent studies add dose-response and anthocyanin-metabolite support for glucose, lipid, inflammation, liver, and microbiome mechanisms.

Limits, risks, and missing evidence

• Human evidence is early and needs larger controlled trials before strong claims.
• Whole-berry powder effects may not translate to isolated anthocyanins, extracts, capsules, jams, or sweetened products.

Risk flags

• early human data
• food matrix specific
• sugar context
• polyphenol product variability
• allergy or gi tolerance

Linked papers, labels, and reviews

1. Effects of Daily Saskatoon Berry Supplementation on Cardiometabolic Health, Gut Microbiota, and Short-Chain Fatty Acids in Healthy Adults
   early_human / mdpi_saskatoon_berry_human_microbiota_2026
   Recent healthy-adult supplementation study linking Saskatoon berry intake to cardiometabolic markers, gut microbiota, and SCFA readouts.
2. Saskatoon Berry on Metabolism and Gut Microbiota in Prediabetes
   clinical_trial_registry / clinicaltrials_saskatoon_berry_nct04809688
   Trial registry context for Saskatoon berry powder, metabolism, and gut-microbiota outcomes.
3. Dose-Responses Relationship in Glucose Lowering and Gut Dysbiosis to Saskatoon Berry Powder Supplementation in High Fat-High Sucrose Diet-Induced Insulin Resistant Mice
   preclinical / pmc_saskatoon_berry_dose_response_mouse_2021
   Mouse dose-response study for Saskatoon berry powder, glucose/lipid/inflammation markers, and gut dysbiosis.
4. Impact of anthocyanin component and metabolite of Saskatoon berry on gut microbiome and relationship with fecal short chain fatty acids in diet-induced insulin resistant mice
   preclinical / sciencedirect_saskatoon_berry_scfa_mouse_2023
   Mouse study connecting Saskatoon berry anthocyanins/metabolites to gut microbiome and fecal SCFA patterns.