• Clonidine (approved / labelled) - withdrawal
• Dexmedetomidine (approved / labelled) - ICU
• ARA-290 / Cibinetide (early human) - pain
• NAD+ / Intravenous NAD (early human) - addiction
• Batatasin III (preclinical) - pain
• Dermorphin (preclinical) - opioid, pain
• SR-17018 (preclinical) - opioid, pain, withdrawal research